Wake Forest University Baptist Medical Center (WFUBMC), one of the nation's preeminent academic medical centers, is an integrated health care system that operates 1,238 acute care, rehabilitation and long-term care beds, outpatient services, and community health and information centers. The Medical Center has 23 subsidiary or affiliate hospitals and operates more than 100 outreach activities throughout the region, including satellite clinics, health fairs, consulting services and medical director services. It provides a continuum of care that includes primary care centers, outpatient rehabilitation, dialysis centers, and home health care.

Although its primary service area is a 26-county region in northwestern North Carolina and southwestern Virginia, the Medical Center in the year 2007 served patients from 97 (of 100) North Carolina counties, 49 states, the District of Columbia and several foreign countries.